Claim C-0002

In adults, long-term exposure to fine particulate matter (PM₂.₅) is associated with newly diagnosed atopic dermatitis; a second systematic review, based on self-reported exposure and self-reported skin effects, found no association.

Structure

Factor: Particulate matter (PM₂.₅ and PM₁₀)
Outcome: Atopic dermatitis (eczema)
Population: adults
Relation: increases · odds ratio 2.30 (95 % CI 1.25–4.25) per 10 µg/m³
Evidence grade: B · mixed
Caveat: the exposure measured is outdoor air; the grade table would allow A for a systematic review, but the picture is mixed, so the Claim is kept one step lower; the counter-evidence F-0011 is itself a document whose conclusion overstates its own numbers (both summary odds ratios include 1) - it weighs as a null result, not as a positive one

Based on

Finding F-0001: “Exposures to particulate matter < 2.5 μm in diameter (PM2.5) and NO2 were associated with incident AD, with ORs of 2.30 (95% CI: 1.25, 4.25) and 1.30 (95% CI: 1.04, 1.61) per 10 μg/m3 increase respectively.” (CKB 0637, p. 4)

Counter-evidence

Finding F-0011: “According to people’s reports of exposure and negative skin effects (atopic dermatitis (AD), eczema, and skin aging, etc.) due to air pollution, the summary relative risk (odds ratio) of PM10 was determined to be 0.99 (95% confidence interval (CI) 0.89–1.11) whereas PM2.5 was determined to be 1.04 (95% CI 0.96–1.12).” (CKB 0613, p. 1)

A Claim is Coridum’s synthesis of Findings and Observations; the evidence grade follows the study designs behind it.