Finding F-0394

“Adjusted dCO2 prevalence odds ratios for sore throat and wheeze were 1.17 and 1.20 per 100-ppm increase in dCO2 (p <0.05), respectively.”

Indoor carbon dioxide concentrations and sick building syndrome symptoms in the BASE… (2002). Page 1. CKB 0333

Structure

Factor: Carbon dioxide (CO₂)
Outcome: Wheeze
Population: office workers
Setting: office, US
Study design: cross-sectional analysis of the 100-building 1994-1998 USEPA BASE office dataset: workday time-averaged indoor minus outdoor CO2 (dCO2) against sick building syndrome symptoms, multivariate logistic regression adjusted for age, sex, smoking, carpet, thermal exposure and a marker of entrained automobile exhaust (class 4)
Effect: OR 1.20 per 100 ppm
Caveat: prevalence odds ratio; CO2 here is a marker of ventilation rate per person

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