Finding F-1294

“Based on logistic regression models, each IQR increase in O3 concentration was significantly associated with elevated risks of term LBW (RR 1.055, 95% CI 1.034-1.077) and SGA (RR 1.037, 95% CI: 1.026-1.048).”

Gestational Hypertension as a Mediator of Prenatal Ozone Exposure and Term Low Birth… (2026). JMIR Public Health Surveill. Page 5. CKB 1572

Structure

Factor: Ozone (O₃)
Outcome: Low birth weight
Population: pregnant women and their term births
Setting: city (ambient), CN
Study design: cohort of 113,382 births in Shandong Province, China, between 2016 and 2022: ozone, particulate matter, carbon monoxide, nitrogen dioxide, sulfur dioxide and temperature during pregnancy estimated at the mother's address and related to term low birth weight and small for gestational age with logistic regression, Cox proportional hazards models and a mediation analysis through gestational hypertension (class 3)
Effect: RR 1.055 (1.034–1.077) per 1
Caveat: outdoor ozone estimated at the address, not an indoor measurement; the interquartile range of the study is 19.93 μg/m3 around a median of 112.70 μg/m3

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