Health outcome · disease
Stroke
Part of: Cardiovascular disease (CVD)
Also: cerebrovascular accident, ischaemic stroke, haemorrhagic stroke, cerebrovascular disease
Sudden loss of brain function caused by interruption of its blood supply or by bleeding into it. It enters indoor air research as one of the two hard cardiovascular endpoints, reached through the same vascular pathways as heart disease.
Not reviewed by a clinician. This entry describes a disease or a symptom. We are introducing clinical review for pages of this kind; until that reviewer is in place, this page has been written and checked by the Coridum team but not reviewed by a clinician. It is general information and not medical advice. How this library is built is described in How we build this library.
Why it matters indoors
Stroke is an outcome that cannot be missed: it is disabling or fatal, it reaches a hospital, and it is recorded. That makes it usable in the large cohorts where household exposures are studied over decades, and it is one of the endpoints through which household air pollution is assigned a share of global mortality.
The route from air to brain runs through the vessels. Fine particles provoke systemic inflammation, raise blood pressure, and promote the changes in clotting and vessel wall that precede an arterial event — the same chain that connects the exposure to heart disease, which is why the two are usually reported together.
Household evidence comes mainly from cohorts comparing cooking and heating fuel, where risk rises with the number of years a household used solid fuel. The exposure in such studies is a household characteristic rather than a measurement, and the caveat says so.
Indoor factors with evidence
| Factor | Effect | Population | Study design | Source | Checked |
|---|---|---|---|---|---|
| Particulate matter (PM₂.₅ and PM₁₀) | HR 1.09 (1.06–1.12) per 10 | — | systematic review and meta-analysis of 38 publications (35 cohort and 3 case-control studies) on long-term particulate matter exposure in low- and middle-income countries; preprint (Research Square), not peer reviewed | F-0070 The chronic effects of particulate matter (PM2.5, PM10 and P… (2022) | machine |
| Solid fuel | OR 1.87 (1.03–3.38) | — · home | cross-sectional study of adults: in-home solid fuel exposure and its duration related to hypertension, coronary heart disease, stroke and diabetes, adjusted for potential confounders | F-1709 Lee In-home solid fuel use and cardiovascular disease: a cross-s… (2012) | machine |
Each row is one Finding — a sentence as printed in one study, recorded with its page in the Coridum Knowledge Base. Follow the Finding number for the exact wording and the citation. Checked says who verified the row: machine means every automatic check passed and the surrounding text was read; person means someone read the sentence in the document. Rows are re-checked by a person over time. The studies are curated in the Coridum Knowledge Base; the reading of them together is a Claim, shown separately.
Cite this page
Coridum Research. Stroke. Coridum Knowledge G-0173, 16 September 2026. https://coridum.com/k/G-0173/